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DeepMind AlphaFold team members, a diverse group of scientists, in a laboratory setting, discussing their groundbreaking prot

Editorial illustration for DeepMind AlphaFold team disbands as researchers depart for Anthropic, Isomorphic

AlphaFold Team Disbands as Researchers Leave DeepMind

4 min read

Google DeepMind has dismantled the team that built AlphaFold, the protein-structure prediction system that won John Jumper and Demis Hassabis the 2024 Nobel Prize in Chemistry. The Financial Times reports that most of the researchers who authored the original AlphaFold papers were reassigned to other projects over the past year, and nearly a quarter of them have left the company entirely. Some moved to Isomorphic Labs, the Alphabet drug-discovery spinout with deals already in place with Novartis and Eli Lilly. Others shifted to work tied to Gemini, plus enzyme design, nuclear fusion and genomics.

DeepMind confirmed the moves. AlphaFold, in development since 2018, had stood as the clearest proof of concept for the lab's approach: pick a hard scientific problem, build a dedicated team, chase it for years. That model turned DeepMind into a scientific powerhouse well beyond its reputation in game-playing AI.

Breaking up the team behind its signature result marks a real departure from that playbook, at a moment when the company is folding more of its research effort into large language models and commercial partnerships. Pushmeet Kohli, DeepMind's vice president of research, laid out the thinking behind the shift.

The majority of the researchers behind AlphaFold are now working on other projects, and almost a quarter have left Google Deepmind altogether. The restructuring marks a sharp turn away from the strategy that put the lab on the map.

Why this matters

Google DeepMind built its reputation on AlphaFold, and now the team that made it is scattering just as the underlying talent becomes the asset everyone else wants. Isomorphic Labs absorbing researchers makes sense on paper: Alphabet gets to keep the expertise in-house while pointing it at drug discovery deals with Novartis and Eli Lilly. But a quarter of the original authors leaving for Anthropic and elsewhere is a different signal entirely.

That's not internal reallocation, that's people choosing to work somewhere else. For researchers watching this, the lesson is blunt: even a landmark scientific result doesn't guarantee your team stays intact or that the lab keeps betting on the same approach. For founders and developers building on AlphaFold's methods or hoping to hire from that talent pool, the dispersal means the institutional knowledge is now spread across at least three organizations with different incentives and different masters.

Worth watching whether DeepMind names a successor project, or whether this is simply an admission that the AlphaFold era, as a DeepMind-owned story, is over.

Common Questions Answered

Why did Google DeepMind disband the AlphaFold team?

Google DeepMind dismantled the AlphaFold team by reassigning most researchers to other projects over the past year, marking a strategic shift away from the protein-structure prediction work that originally built the lab's reputation. The restructuring reflects a broader reallocation of resources within the organization rather than a single decisive event.

Where did the AlphaFold researchers go after leaving Google DeepMind?

Nearly a quarter of the original AlphaFold team members left Google DeepMind entirely, with some moving to Anthropic and others joining Isomorphic Labs, the Alphabet drug-discovery spinout. Isomorphic Labs, which already has deals in place with pharmaceutical companies like Novartis and Eli Lilly, absorbed a significant portion of the departing researchers to focus on drug discovery applications.

What recognition did the AlphaFold team receive for their work?

The AlphaFold team's groundbreaking contributions to protein-structure prediction were recognized with the 2024 Nobel Prize in Chemistry, awarded to John Jumper and Demis Hassabis. This prestigious honor highlighted the significance of the team's achievements in computational biology and structural biology.

How does the departure of AlphaFold researchers to Anthropic differ from their move to Isomorphic Labs?

While some researchers moved to Isomorphic Labs, an Alphabet-owned spinout that keeps the expertise within the company for drug discovery partnerships, the departure of a quarter of the original authors to Anthropic and other external companies represents a more significant loss of talent outside Google's ecosystem. This external brain drain signals a different challenge than internal reallocation, as the expertise becomes available to competitors rather than remaining within Alphabet's portfolio.

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